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Singapore Clinical Trial: Using AS01 adjuvant to improve immune response in older adults through trained immunity

Singapore, July 31 -- The Health Sciences Authority received information related to the study titled 'Using AS01 adjuvant to improve immune response in older adults through trained immunity'. The foll... Read More


Singapore Clinical Trial: A Phase 1 Dose Escalation Trial to Determine the Safety, Tolerance, Maximum Tolerated Dose,and Preliminary Antineoplastic Activity of IKS014, a HER2-Targeting Antibody Drug Conjugate(ADC), in Participants with Advanced HER2+ Solid Tumors

Singapore, July 31 -- The Health Sciences Authority received information related to the study titled 'A Phase 1 Dose Escalation Trial to Determine the Safety, Tolerance, Maximum Tolerated Dose,and Pre... Read More


Singapore Clinical Trial: A Phase 3 Randomized, Open-label Study to Evaluate the Efficacy and Safety of sac-TMT (Sacituzumab Tirumotecan, MK-2870) Followed by Carboplatin/Paclitaxel vs Chemotherapy, Both in Combination With Pembrolizumab as Neoadjuvant Therapy for High-Risk, Early-Stage, Triple-Negative Breast Cancer or Hormone Receptor-low Positive/Human Epidermal Growth Factor Receptor-2 Negative Breast Cancer

Singapore, July 31 -- The Health Sciences Authority received information related to the study titled 'A Phase 3 Randomized, Open-label Study to Evaluate the Efficacy and Safety of sac-TMT (Sacituzumab... Read More


Singapore Clinical Trial: A Phase 3, Open-label, Multicenter, Randomized Study of Xaluritamig Plus Abiraterone Versus Investigator’s Choice in Participants with Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

Singapore, July 31 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, Open-label, Multicenter, Randomized Study of Xaluritamig Plus Abiraterone Versus Invest... Read More


Singapore Clinical Trial: Regime for vitamin D maintEnanCe In poSt-operatIVE patients (D-ECISIVE) Randomized Controlled Trial

Singapore, July 31 -- The Health Sciences Authority received information related to the study titled 'Regime for vitamin D maintEnanCe In poSt-operatIVE patients (D-ECISIVE) Randomized Controlled Tria... Read More


Singapore Clinical Trial: A Phase 1, Open-Label, Randomized, Crossover Study to Investigate the Relative Bioavailability of Abemaciclib (LY2835219) Test and Reference Formulations and an Alternate Administration Method, in Healthy Participants

Singapore, July 31 -- The Health Sciences Authority received information related to the study titled 'A Phase 1, Open-Label, Randomized, Crossover Study to Investigate the Relative Bioavailability of ... Read More


Singapore Clinical Trial: Solid tumor Study for Long term Treatment of Cancer Patients Who Have Participated in BMS-Parent Studies Investigating Adagrasib (BMS-986503)

Singapore, July 31 -- The Health Sciences Authority received information related to the study titled 'Solid tumor Study for Long term Treatment of Cancer Patients Who Have Participated in BMS-Parent S... Read More


Singapore Clinical Trial: A Global, Multicentre, Phase II Platform Study of Datopotamab Deruxtecan (Dato-DXd)-based Combinations in Adult Participants With TROP2 NMR-positive Non-small Cell Lung Cancer (NSCLC) (PATAGONIA)

Singapore, July 31 -- The Health Sciences Authority received information related to the study titled 'A Global, Multicentre, Phase II Platform Study of Datopotamab Deruxtecan (Dato-DXd)-based Combinat... Read More


Singapore Clinical Trial: A Phase Ib, Open-Label, Multicenter Study of EBC-129 Combined With Osimertinib in Patients With Advanced EGFR-Mutated, Osimertinib-Resistant Non–Small Cell Lung Cancer (NSCLC)

Singapore, July 31 -- The Health Sciences Authority received information related to the study titled 'A Phase Ib, Open-Label, Multicenter Study of EBC-129 Combined With Osimertinib in Patients With Ad... Read More


Singapore Clinical Trial: ROSETTA Lung-201: A Randomized, Multicenter, Open-label Phase 3 Study of Pumitamig Monotherapy Compared to Durvalumab in Participants with Unresectable Stage III NSCLC Without Progression After Platinum-based Concurrent Chemoradiation Therapy.

Singapore, July 31 -- The Health Sciences Authority received information related to the study titled 'ROSETTA Lung-201: A Randomized, Multicenter, Open-label Phase 3 Study of Pumitamig Monotherapy Com... Read More